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Similarly, there are uncertainties referring to numerous different important factors, including: outcomes of clinical trials and preclinical studies, together with subsequent evaluation of existing data and new knowledge received from ongoing and future studies; the content and timing of choices made by the U.S. FDA and different regulatory authorities, investigational assessment boards at clinical trial websites and publication evaluation bodies; the flexibility to enroll patients in planned medical trials; unplanned money requirements and expenditures; aggressive components; the ability to acquire, keep and implement patent and different intellectual property protection for any product candidates; the ability to take care of key collaborations; and common economic and market conditions.
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